Journal of Integrative Cancer Biology
Molecular Mechanisms of Cancer
Cancer develops due to a series of molecular and genetic alterations that disrupt normal regulation of cell growth, differentiation, and survival. One of the key molecular mechanisms of cancer is activation of oncogenes, which are mutated or overexpressed forms of normal proto-oncogenes that promote uncontrolled cell proliferation. Along with this, inactivation or loss of tumor suppressor genes such as p53 and RB removes critical cell-cycle checkpoints, allowing damaged cells to continue dividing. Defects in DNA repair mechanisms further contribute to genomic instability, leading to accumulation of mutations that drive cancer progression.
Article Processing Timeline
| 2-5 Days | Initial Quality & Plagiarism Check |
| 15 Days |
Peer Review Feedback |
| 85% | Acceptance Rate (after peer review) |
| 30-45 Days | Total article processing time |
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Journal Highlights
Cancer Biology and Tumor Microenvironment
Immuno-oncology and Cancer Vaccines
Translational Cancer Research
Cancer Genomics and Epigenetics
Biomarkers and Liquid Biopsy
Global Cancer Disparities and Public Health
Cancer Survivorship and Palliative Care
Breast, Lung and Colorectal Cancer Research
AI and Imaging in Oncology
Hematologic and Pediatric Oncology
Tumor Microenvironment & Cancer Immunology
Molecular Mechanisms of Cancer
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