About the Journal
The Journal of Molecular Biology is a peer-reviewed, international, open-access journal that provides a premier platform for cutting-edge research at the molecular and cellular levels of biological systems. As science increasingly focuses on understanding life at the most fundamental scale, the Journal of Molecular Biology embraces the full scope of molecular biology, from gene expression and protein folding to RNA technologies, genome editing, cell signaling, and biomolecular interactions. The journal is dedicated to promoting high-quality, reproducible research that deepens our understanding of molecular mechanisms and advances the future of biomedical innovation, biotechnology, and therapeutic development. Journal of Molecular Biology publishes a wide range of scholarly articles, including original research papers, comprehensive reviews, short communications, structural studies, functional genomics analyses, synthetic biology advancements, and computational biology models. Topics of interest include DNA/RNA biology, epigenetics, molecular genetics, proteomics, transcriptomics, systems biology, genome engineering (including CRISPR/Cas systems), gene regulation, molecular pathogenesis, enzymology, structural biology, cell cycle regulation, and molecular mechanisms underlying human diseases such as cancer, neurodegeneration, and metabolic disorders. JMBC also encourages the integration of molecular approaches with advanced imaging, biophysical techniques, nanotechnology, and bioinformatics. Each manuscript submitted to the Journal of Molecular Biology undergoes a rigorous single-blind peer-review process, guided by an expert editorial board to ensure scientific accuracy, novelty, and relevance to a global scientific audience. As an open-access journal, JMBC ensures that all published articles are freely available to researchers, educators, students, and industry professionals worldwide, eliminating access barriers and fostering collaborative scientific advancement. Our editorial mission supports both well-established and early-career scientists, and we particularly welcome interdisciplinary work that bridges traditional life sciences with engineering, physics, and computational methods. The Journal of Molecular Biology is more than a research journal; it is a collaborative arena where molecular discoveries unfold into real-world innovations. In an era where molecular-level insights are transforming drug development, agriculture, bioenergy, and precision medicine, the Journal of Molecular Biology provides a trusted, forward-looking platform for scientists who seek to explore the building blocks of life. Join a global community that values clarity, transparency, innovation, and molecular excellence.
Aim and Scope
The Journal of Molecular Biology publishes high-quality original research articles, reviews, short communications, case studies, and technical notes spanning all major domains of molecular biology and modern biomolecular sciences. We welcome submissions across (but not limited to) the following thematic areas:
Molecular Structure, Dynamics & Biophysics
- Structure and function of proteins, nucleic acids, and macromolecular complexes
- Molecular folding, misfolding, aggregation, and stability
- Protein and RNA dynamics, conformational changes, and energy landscapes
- Cryo-EM, X-ray crystallography, NMR spectroscopy, and single-molecule methods
- Computational modeling, molecular dynamics simulations, structural prediction
Genetics, Genomics & Chromosome Biology
- Gene structure, regulation, and expression
- Genome organization, chromatin architecture, epigenetics, and nuclear dynamics
- High-throughput sequencing, comparative genomics, and population genomics
- Transcriptional control, enhancer biology, and noncoding regulatory elements
- Genetic variation, mutation, recombination, and genome evolution
Molecular Cell Biology
- Cellular signaling pathways and molecular regulatory networks
- Membrane trafficking, organelle dynamics, and cytoskeletal organization
- Cell cycle regulation, DNA replication, repair, and recombination
- Apoptosis, autophagy, senescence, and cellular stress responses
- Cell–cell communication, adhesion, and extracellular matrix interactions
RNA Biology & Gene Regulation
- RNA structure, modification, and function
- Ribosome biology, translation mechanisms, and translational control
- Noncoding RNAs (miRNA, siRNA, lncRNA, circRNA), RNA processing, splicing
- Regulatory RNA networks in development, physiology, and disease
- RNA–protein interactions and RNP complex biology
Proteomics, Metabolomics & Systems Biology
- Proteomic profiling, post-translational modifications, and protein networks
- Metabolomic pathways, metabolic regulation, and biochemical flux analysis
- Quantitative systems biology, network modeling, and data integration
- Multi-omics approaches for functional characterization
- High-throughput technologies and computational biology
Molecular Pathways in Health & Disease
- Molecular mechanisms underlying human diseases
- Oncogenesis, tumor suppressors, signaling dysregulation
- Neurodegenerative, metabolic, cardiovascular, and immune-related disorders
- Host–pathogen interactions at the molecular level
- Biomarker discovery and molecular therapeutic targets
Molecular Biotechnology & Synthetic Biology
- Genetic engineering, gene editing (CRISPR/Cas, base editors, prime editing)
- Molecular cloning, vector design, and recombinant DNA technology
- Synthetic circuits, gene constructs, genome rewriting
- Biomolecular engineering, protein design, and directed evolution
- Industrial, agricultural, environmental, and biomedical biotechnology applications
Bioinformatics, Computational Molecular Biology & AI
- Computational tools for molecular sequence, structure, and interaction analysis
- Machine learning and AI in molecular prediction and design
- Algorithm development, data mining, and biomolecular simulation
- Computational genomics, transcriptomics, and molecular modeling
- Big data analytics and digital molecular biology
Molecular Microbiology & Virology
- Bacterial, archaeal, viral, and microbial eukaryote molecular mechanisms
- Microbial gene regulation, quorum sensing, and metabolic pathways
- Virus structure, replication, host manipulation, and antiviral strategies
- Microbial genomics, pathogenesis, and molecular immunity
Chemical Biology & Biochemical Mechanisms
- Enzyme structure, mechanisms, and catalytic regulation
- Signal transduction cascades and molecular switches
- Small molecules, molecular probes, and chemical modulators of biology
- Natural product mechanisms and bioactive compound discovery
- Molecular interactions, binding kinetics, and energetics
Emerging & Interdisciplinary Molecular Technologies
- Nanobiotechnology, molecular sensors, and biomimetic systems
- High-throughput screening, microfluidics, lab-on-chip technologies
- Single-cell sequencing, spatial omics, and advanced imaging
- Molecular diagnostics, therapeutics, biologics, and precision medicine
- Ethics, policy, biosafety, and responsible innovation in molecular biology
Editorial and Peer-Review Policy
Journal of Molecular Biology employs a single-blind peer-review process to maintain fairness,
scientific integrity, and the quality of published work.
Key Features:
- Every manuscript is assessed by at least two independent subject experts, along with editorial oversight.
- Reviewers can see author details, but the identities of the authors remain hidden from them.
- The review criteria focus on originality, technical strength, methodological accuracy, ethical compliance, clarity, and relevance to the field of nanoscience.
- All submissions go through plagiarism checks and ethical evaluations before the peer-review process.
- Final decisions on publication are made by the handling editor, based on the reviewers' evaluations and the overall quality of the manuscript.
Publication Frequency & Format
This journal comes out three times a year. Once articles are accepted, they're quickly made available online in both HTML and PDF formats, ensuring fast and easy access to research findings.
Open Access Policy
Journal of Molecular Biology embraces a gold open access model, meaning all published articles are freely accessible to everyone. Authors retain the copyright to their work, shared under a suitable open-access license to promote transparency, collaboration, and global knowledge-sharing.
Indexing & Archiving
The journal aims to be included in well-known scientific indexing and abstracting databases. All content is preserved through trusted archiving systems to ensure long-term accessibility and discoverability.
For Manuscript Submission
Authors can submit their manuscripts through the journal's Online Submission System
(Submit Manuscript) or by emailing the Editorial Office at
support@globalmeetx.com.
Submitted manuscripts must adhere to the Journal of Molecular Biology Author Guidelines, which cover structure, formatting,
ethical approvals, and conflict-of-interest disclosures.
Publication Ethics & Integrity
Journal of Molecular Biology is committed to maintaining the highest publication ethics standards in accordance with COPE principles.
Authors must ensure proper ethical approvals for studies involving humans, animals, or sensitive materials, and follow informed consent and confidentiality practices.
They must also disclose conflicts of interest and funding support, report data accurately, and acknowledge contributor roles.
All submissions undergo plagiarism checks, and the journal has a strict policy for corrections, retractions, and post-publication updates.
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