Global Cancer Disparities and Public Health address the unequal burden of cancer across different populations and regions. Cancer outcomes vary significantly due to differences in healthcare access, socioeconomic status, education, environmental exposures, and availability of early detection and treatment services. Low- and middle-income countries often face higher mortality rates because of limited resources, late diagnoses, and insufficient infrastructure for cancer care. Public health initiatives aim to reduce these disparities through cancer awareness, vaccination programs, affordable screening, and equitable access to care. Strengthening cancer registries, improving healthcare systems, and investing in prevention strategies are essential to closing the gap. Addressing global cancer disparities is vital for ensuring that all individuals, regardless of location or background, receive timely, effective, and life-saving cancer care.