Clinical Decision Support Systems (CDSS) use AI, analytics, and medical knowledge bases to assist healthcare professionals in making accurate and timely clinical decisions. These systems analyze patient data, lab results, symptoms, and medical history to generate alerts, recommendations, and diagnostic insights. CDSS help identify potential drug interactions, suggest treatment options, and flag critical abnormalities. Integrated with EHRs, they improve workflow efficiency and reduce diagnostic errors. By providing evidence-based guidance at the point of care, clinical decision-support systems enhance patient safety, support personalized treatment, and strengthen overall clinical outcomes.