Craniofacial Anomalies refer to congenital or acquired deformities affecting the bones and soft tissues of the skull and face. This field involves the diagnosis, surgical correction, and long-term management of conditions such as cleft lip and palate, craniosynostosis, hemifacial microsomia, Treacher Collins syndrome, and other syndromic and non-syndromic facial malformations. Treatment requires a multidisciplinary approach, involving craniofacial surgeons, orthodontists, neurosurgeons, geneticists, and speech therapists to ensure optimal functional and aesthetic outcomes. Advances in 3D imaging, surgical planning, distraction osteogenesis, and tissue engineering have revolutionized craniofacial reconstruction. Early intervention, combined with long-term developmental follow-up, is key to improving speech, breathing, feeding, and psychosocial well-being. Research in this area also explores regenerative strategies and genetic pathways to better understand and treat craniofacial disorders.