Journal of Molecular Biology

Dr. Madhumita P. Ghosh is an Associate Professor at the Amity Institute of Biotechnology, Amity University, Noida. She earned her Ph.D. in Biotechnology from Jadavpur University, Kolkata in 2001. She conducted her postdoctoral research at the National Eye Institute (NIH, Bethesda, USA) under the mentorship of Dr. Samuel Zigler Jr., focusing on ocular disease mechanisms and cataractogenesis models.

She later worked at the National Brain Research Center (NBRC), New Delhi, where she investigated retinal degeneration models in mice. Since joining Amity University in 2008, Dr. Ghosh has progressed from Senior Lecturer to Associate Professor, contributing extensively to teaching and research in Animal Biotechnology and Immunology.

Her research primarily explores neuroprotection and retinal degeneration, focusing on antioxidant therapies, neuroprotective nanoformulations, and retinal precursor stem cell therapy. She has successfully led multiple DBT, DST-SERB, and ICMR-funded projects, and mentored several Ph.D. students.

Dr. Ghosh has published widely in reputed journals such as Experimental Eye Research, Nature Scientific Reports, Biomedicine & Pharmacotherapy, Molecular Vision, Toxicology Letters, ACS Applied Biomaterials, and Journal of Biomolecular Structure and Dynamics. Her work has made significant contributions to understanding oxidative stress, excitotoxicity, and neuroprotective drug delivery for ocular diseases.

• etinal degeneration and neuroprotection
• Retinal stem cell culture and precursor cell therapy
• Dopamine and IGF-1 signaling in angiogenesis

• Principal Investigator of multiple funded projects from DBT, DST-SERB, and ICMR
• Mentor and Supervisor of Ph.D. scholars in neuro-ophthalmic research
• Invited Speaker at international and national conferences including:
• Cell Science 2024 (Rome, Italy)
• Indian Academy of Neuroscience (2023–2024)
• Conference on Neurological Disorders and Stroke 2023 (Rome, Virtual)
• Life Member of:
• Indian Academy of Neuroscience
• India Eye Research Group
• Vitreo Retina Society of India
• Awards:
• Women Researcher Award (Neurology 2024, Berlin)
• Poster Award (Advances in Biosciences & Biotechnology, 2022)

• Hadwani K, Chaturvedi S, Kumaran SS, Kumari S, Singh J, Ghosh MP, Basu T. Breaking the Gadolinium Mold: A Metal-Organic Framework Contrast Agent for MRI. ACS Applied Bio Materials. 2025.

• Upreti S, Sharma P, Sen S, Biswas S, Ghosh MP. Auxiliary effect of trolox on coenzyme Q10 restricts angiogenesis and proliferation of retinoblastoma cells via ERK/Akt pathway. Scientific Reports. 2024.

• Shaw S, et al., Ghosh MP. Molecular interaction of quercetin and derivatives against nucleolin in breast cancer. J. Biomolecular Structure & Dynamics. 2024.

• Upreti S, Nag TC, Ghosh MP. Trolox aids CoQ10 in neuroprotection against NMDA-induced damage in rat retina. Experimental Eye Research. 2024.

• Upreti S, Sen S, Nag TC, Ghosh MP. Dopamine and IGF-1 synergistically attenuate diabetic retinopathy. Biomedicine & Pharmacotherapy. 2022.

• Kaur A, Sharma Y, Kumar A, Ghosh MP, Bala K. In-vitro antiproliferative efficacy of Abrus precatorius seed extracts. Scientific Reports. 2022.

• Chansi, Upreti S, Ghosh MP, Basu T. Rapid Electrochemical Quantification for Ophthalmic Drug Release from MOF. ChemistrySelect. 2021.