Journal of Molecular Biology

Esdras Matheus Gomes da Silva holds a Bachelor's degree in Biological Sciences, a Master’s, and a Ph.D. in Computational and Systems Biology from Fiocruz. He specializes in Bioinformatics, focusing on high-throughput sequencing data (genomics, RNA-seq, proteomics). He is currently a postdoctoral researcher at the Institute of Biosciences, University of São Paulo (USP), working in the Amphibian Laboratory. His research investigates the diversity of antimicrobial peptides produced by anurans, combining computational and experimental methods to explore their biotechnological and therapeutic potential.

• Biotechnology
• Machine Learning
• RNA-Seq
• Genomics
• Mass Spectrometry–based Proteomics (tandem MS)
• Proteogenomics
• Bioinformatics

1. Linux server administration

2. Extraction of hDNA and sequencing library preparation

3. Building pipelines for mitochondrial genome assembly

4. Molecular phylogenetic analysis

5. Proteogenomics research

6. Investigation of antimicrobial peptides in amphibians

1. Museomics reduces taxonomic inflation in the Dendropsophus araguaya complex — 2025

2. Genetic Variants Affect Distinct Metabolic Pathways in Pediatric MIS and Severe COVID-19 — 2025

3. SpliceProt 2.0: A Sequence Repository of Human, Mouse, and Rat Proteoforms — 2024

4. Identification of Novel Genes and Proteoforms in Angiostrongylus costaricensis through a Proteogenomic Approach — 2022

5. Proteogenomics reveals orthologous alternatively spliced proteoforms… in Alzheimer’s Disease Mouse Model — 2021

6. The Challenge to Search for New Nervous System Disease Biomarker Candidates: the Opportunity to Use the Proteogenomics Approach — 2019