Cancer Screening and Early Detection play a critical role in reducing cancer-related mortality by identifying the disease at an early, more treatable stage. Screening involves routine testing of individuals who may not show symptoms but are at risk due to age, genetics, or lifestyle factors. Common screening methods include mammography for breast cancer, colonoscopy for colorectal cancer, Pap smears for cervical cancer, and low-dose CT scans for lung cancer in high-risk groups. Early detection allows for timely intervention, increasing the chances of successful treatment and survival. Advances in biomarkers, imaging technologies, and non-invasive tests such as liquid biopsies are further enhancing detection accuracy. Promoting awareness and accessibility of screening programs is essential for improving public health and minimizing the global burden of cancer.