3D Bioprinting & Tissue Engineering Scaffolds represent cutting-edge technologies in regenerative medicine aimed at fabricating functional biological tissues and organs. 3D bioprinting uses computer-guided deposition of bioinks—composed of living cells, biomaterials, and growth factors—to build tissue constructs layer-by-layer with high precision. Tissue engineering scaffolds serve as structural frameworks that support cell adhesion, proliferation, and differentiation, ultimately guiding tissue regeneration. These scaffolds can be fabricated from natural polymers (e.g., collagen, alginate) or synthetic materials (e.g., PLGA, PCL), and are often designed to mimic the extracellular matrix. Applications range from skin and bone regeneration to complex structures like blood vessels, cartilage, and organs. Research continues to optimize scaffold properties such as porosity, biodegradability, and mechanical strength, while integrating vascularization and innervation for enhanced functionality in clinical transplantation.